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Tzu-Hsuan Huang Selected Research

Neoplasms (Cancer)

1/2022Molecular interaction mechanisms of glycol chitosan self-healing hydrogel as a drug delivery system for gemcitabine and doxorubicin.
10/2021An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity.
1/2019Empowering therapeutic antibodies with IFN-α for cancer immunotherapy.
12/2018Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.
1/2017Identification of novel resistance mechanisms to NAMPT inhibition via the de novo NAD+ biosynthesis pathway and NAMPT mutation.
3/2015HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer.
1/2014Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells.
6/2013Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
9/2010RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus.
7/2009Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.
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Tzu-Hsuan Huang Research Topics

Disease

11Neoplasms (Cancer)
01/2022 - 11/2007
3Breast Neoplasms (Breast Cancer)
03/2015 - 07/2009
1Experimental Melanoma
10/2021
1Alzheimer Disease (Alzheimer's Disease)
01/2021
1Triple Negative Breast Neoplasms
12/2018
1Fibrosarcoma
01/2017
1Carcinoma (Carcinomatosis)
03/2015
1Lung Neoplasms (Lung Cancer)
03/2015
1Tuberous Sclerosis 1
02/2010
1Carcinogenesis
02/2010
1Neoplasm Metastasis (Metastasis)
07/2009
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2007

Drug/Important Bio-Agent (IBA)

2Pharmaceutical PreparationsIBA
01/2022 - 12/2018
2Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2007
2Epidermal Growth Factor (EGF)IBA
12/2018 - 09/2010
2Phosphotransferases (Kinase)IBA
03/2015 - 06/2013
2ErbB Receptors (EGF Receptor)IBA
01/2014 - 06/2013
1GemcitabineFDA Link
01/2022
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022
1Drug CarriersIBA
01/2022
1HydrogelsIBA
01/2022
1Interleukin-15 (Interleukin 15)IBA
10/2021
1Protein Tyrosine PhosphatasesIBA
01/2021
1AntigensIBA
01/2019
1AntibodiesIBA
01/2019
1Programmed Cell Death 1 ReceptorIBA
12/2018
1B7-H1 AntigenIBA
12/2018
1TransferasesIBA
12/2018
1NAD (NADH)IBA
01/2017
1N- (6- chlorophenoxyhexyl)- N''- cyano- N''- 4- pyridylguanidine (CHS 828)IBA
01/2017
1Tyrosine Kinase InhibitorsIBA
03/2015
1Tyrosine (L-Tyrosine)FDA Link
06/2013
1Cyclin D1IBA
09/2010
1TOR Serine-Threonine KinasesIBA
02/2010
1MicroRNAs (MicroRNA)IBA
07/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2009
1Cell Surface ReceptorsIBA
07/2009
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
07/2009
1Immunoglobulin G (IgG)IBA
11/2007

Therapy/Procedure

2Immunotherapy
10/2021 - 01/2019
1Therapeutics
03/2015
1Drug Therapy (Chemotherapy)
01/2014